Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3843547 | 0.89 | ALPL (0.46) | NPC1RAB9ASMN1; SMN2ALPLP2RX7 | |
| SCHEMBL28115946 | 0.83 | FFAR4 (0.51) | NPC1RAB9ASMN1; SMN2ALPLTDP1 | |
| SCHEMBL8501897 | 0.81 | ALPL (0.43) | NPC1RAB9ASMN1; SMN2ALPLF2 | |
| SCHEMBL8503078 | 0.81 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2ALPLF2 | |
| SCHEMBL28229836 | 0.80 | ALPL (0.47) | NPC1RAB9ASMN1; SMN2ALPLP2RX7 | |
| SCHEMBL1286018 | 0.79 | ALPL (0.48) | NPC1RAB9ASMN1; SMN2ALPLTDP1 | |
| SCHEMBL3838606 | 0.79 | ALPL (0.46) | NPC1RAB9ASMN1; SMN2ALPLP2RX7 | |
| SCHEMBL19912237 | 0.77 | ALPL (0.45) | NPC1RAB9ASMN1; SMN2ALPLP2RX7 | |
| SCHEMBL3842506 | 0.77 | ALPL (0.45) | NPC1RAB9ASMN1; SMN2ALPLP2RX7 | |
| SCHEMBL3843434 | 0.75 | GAA (0.43) | SMN1; SMN2ALDH1A1MAPTGAAFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180057685-A1 | FLAME-RETARDANT RESIN COMPOSITION | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2018-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180057685-A1 | FLAME-RETARDANT RESIN COMPOSITION | PRPF4, RPL4, PSMB4 | NPC1 4200/4885RAB9A 3310/4885SMN1; SMN2 865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.