Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28299311 | 0.87 | ESR2 (0.52) | ESR2ALOX5APFEN1CYP11B1CYP11B2 | |
| SCHEMBL19579103 | 0.85 | ESR2 (0.50) | ESR2ALOX5APFEN1CYP11B1CYP11B2 | |
| SCHEMBL13614777 | 0.85 | CYP11B1 (0.50) | ALOX5APFEN1CYP11B1CYP11B2GABRG2 | |
| SCHEMBL30415829 | 0.85 | CYP11B1 (0.50) | ALOX5APFEN1CYP11B1CYP11B2GABRG2 | |
| SCHEMBL21960122 | 0.84 | ALOX5AP (0.55) | ESR2ALOX5APFEN1CYP11B1CYP11B2 | |
| SCHEMBL1373319 | 0.80 | ALOX5AP (0.45) | ESR2ALOX5APFEN1CYP11B1CYP11B2 | |
| SCHEMBL2775651 | 0.80 | ESR2 (0.53) | ESR2ALOX5APFEN1CYP11B1CYP11B2 | |
| SCHEMBL1372803 | 0.77 | ALOX5AP (0.52) | ESR2ALOX5APFEN1CYP11B1CYP11B2 | |
| SCHEMBL20616784 | 0.77 | AR (0.58) | ALOX5APFEN1TRPV4TRPA1AR | |
| SCHEMBL24085014 | 0.76 | ESR2 (0.52) | ESR2ALOX5APFEN1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504200-B1 | HETEROCYCLICALLY SUBSTITUTED BIPHENYLS, ESPECIALLY FOR USE IN OPTOELECTRONIC APPARATUSES | CYNORA GMBH (DE) | 2021-01-20 | — | — | EP | disclosed |
| WO-2018037069-A1 | HETEROCYCLICALLY SUBSTITUTED BIPHENYLS, ESPECIALLY FOR USE IN OPTOELECTRONIC APPARATUSES | CYNORA GMBH (DE) | 2018-03-01 | — | — | WO | disclosed |