Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | USP8 | P40818 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19917543 | 0.87 | ESR2 (0.50) | ESR2ALOX5APFEN1CYP11B1CYP11B2 | |
| SCHEMBL19579103 | 0.87 | ESR2 (0.50) | ESR2ALOX5APFEN1CYP11B1CYP11B2 | |
| SCHEMBL21960122 | 0.85 | ALOX5AP (0.55) | ESR2ALOX5APFEN1CYP11B1CYP11B2 | |
| SCHEMBL1373319 | 0.81 | ALOX5AP (0.45) | ESR2ALOX5APFEN1CYP11B1CYP11B2 | |
| SCHEMBL2775651 | 0.81 | ESR2 (0.53) | ESR2ALOX5APFEN1CYP11B1CYP11B2 | |
| SCHEMBL1372803 | 0.79 | ALOX5AP (0.52) | ESR2ALOX5APFEN1CYP11B1CYP11B2 | |
| SCHEMBL17840122 | 0.79 | FEN1 (0.42) | ALOX5APFEN1AR | |
| SCHEMBL24085014 | 0.78 | ESR2 (0.52) | ESR2ALOX5APFEN1CYP11B1CYP11B2 | |
| SCHEMBL19579267 | 0.78 | ESR2 (0.47) | ESR2ALOX5APFEN1CYP11B1CYP11B2 | |
| SCHEMBL19579264 | 0.78 | USP8 (0.47) | ESR2ALOX5APFEN1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761820-B | Chemical synthesis method of 3',4',5 '-trifluoro- [1,1' -biphenyl ] -2-amine | 浙江工业大学 | 2022-03-25 | — | — | CN | claimed |
| CN-109761820-A | A kind of 3`, 4`, the chemical synthesis process of fluoro- [1,1`- the biphenyl] -2- amine of 5`- tri- | 浙江工业大学 | 2019-05-17 | — | — | CN | claimed |
| CN-117285426-A | Method for simultaneously preparing biphenyl bactericides and topramezone herbicide intermediates | 帕潘纳(北京)科技有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-109761820-B | Chemical synthesis method of 3',4',5 '-trifluoro- [1,1' -biphenyl ] -2-amine | 浙江工业大学 | 2022-03-25 | — | — | CN | disclosed |