Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.55 |
| ▸ | FEN1 | P39748 | 2/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28299311 | 0.85 | ESR2 (0.52) | ALOX5APFEN1ESR2CYP11B1CYP11B2 | |
| SCHEMBL19917543 | 0.84 | ESR2 (0.50) | ALOX5APFEN1ESR2CYP11B1CYP11B2 | |
| SCHEMBL19579103 | 0.84 | ESR2 (0.50) | ALOX5APFEN1ESR2CYP11B1CYP11B2 | |
| SCHEMBL2648336 | 0.79 | ESR2 (0.46) | ALOX5APFEN1ESR2CYP11B1CYP11B2 | |
| SCHEMBL2653323 | 0.79 | ALOX5AP (0.56) | ALOX5APFEN1ESR2CYP11B1CYP11B2 | |
| SCHEMBL1373319 | 0.78 | ALOX5AP (0.45) | ALOX5APFEN1ESR2CYP11B1CYP11B2 | |
| SCHEMBL2775651 | 0.78 | ESR2 (0.53) | ALOX5APFEN1ESR2CYP11B1CYP11B2 | |
| SCHEMBL1337677 | 0.77 | FEN1 (0.47) | ALOX5APFEN1CYP11B1CYP11B2TRPA1 | |
| SCHEMBL7709223 | 0.76 | ESR2 (0.50) | ALOX5APFEN1ESR2GABRG2GABRB3 | |
| SCHEMBL1372803 | 0.76 | ALOX5AP (0.52) | ALOX5APFEN1ESR2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10858383-B2 | Remote heteroaryl alkenylation with catalytic bifunctional template | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-12-08 | — | — | US | disclosed |
| US-20200131213-A1 | Remote Heteroaryl Alkenylation With Catalytic Bifunctional Template | THE SCRIPPS RESEARCH INSTITUTE | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131213-A1 | Remote Heteroaryl Alkenylation With Catalytic Bifunctional Template | APEH, ALKBH3, JMJD7 | ALOX5AP 1478/4885FEN1 1290/4885ESR2 2694/4885 |
| US-10858383-B2 | Remote heteroaryl alkenylation with catalytic bifunctional template | APEH, ALKBH3, JMJD7 | ALOX5AP 1478/4885FEN1 1290/4885ESR2 2694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.