Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21546867 | 0.97 | ADRA2C (0.36) | GRIN1GRIN2BPDK2MAP4K4ESR2 | |
| SCHEMBL19917592 | 0.97 | GRIN1 (0.37) | GRIN1GRIN2BPDK2MAP4K4ESR2 | |
| SCHEMBL21547013 | 0.93 | ADRA2C (0.38) | GRIN1GRIN2BPDK2MAP4K4ESR2 | |
| SCHEMBL19917563 | 0.92 | ESR2 (0.35) | ESR2CYP1A2CYP3A4KDM4EMEN1 | |
| SCHEMBL22761131 | 0.91 | GRIN1 (0.34) | GRIN1GRIN2BPDK2MAP4K4ESR2 | |
| SCHEMBL19917520 | 0.91 | ESR2 (0.36) | PDK2ESR2CYP1A2CYP3A4KDM4E | |
| SCHEMBL21547012 | 0.90 | GRIN1 (0.37) | GRIN1GRIN2BPDK2ESR2SMN1; SMN2 | |
| SCHEMBL19917589 | 0.90 | GRIN1 (0.39) | GRIN1GRIN2BPDK2MAP4K4ESR2 | |
| SCHEMBL19917591 | 0.90 | GRIN1 (0.33) | GRIN1GRIN2BPDK2SMN1; SMN2HIF1A | |
| SCHEMBL19917613 | 0.90 | ESR2 (0.35) | ESR2SMN1; SMN2HIF1ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504200-B1 | HETEROCYCLICALLY SUBSTITUTED BIPHENYLS, ESPECIALLY FOR USE IN OPTOELECTRONIC APPARATUSES | CYNORA GMBH (DE) | 2021-01-20 | — | — | EP | disclosed |
| WO-2018037069-A1 | HETEROCYCLICALLY SUBSTITUTED BIPHENYLS, ESPECIALLY FOR USE IN OPTOELECTRONIC APPARATUSES | CYNORA GMBH (DE) | 2018-03-01 | — | — | WO | disclosed |