Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21414290 | 0.97 | CYP1A2 (0.37) | ESR2CYP1A2CYP3A4HSD17B10HPGD | |
| SCHEMBL19917564 | 0.97 | ESR2 (0.38) | ESR2CYP1A2CYP3A4HSD17B10HPGD | |
| SCHEMBL19917515 | 0.93 | ESR2 (0.35) | ESR2CYP1A2CYP3A4HSD17B10HPGD | |
| SCHEMBL21414289 | 0.93 | CYP1A2 (0.39) | ESR2CYP1A2CYP3A4HSD17B10HPGD | |
| SCHEMBL19917586 | 0.92 | GRIN1 (0.36) | ESR2CYP1A2CYP3A4HSD17B10HPGD | |
| SCHEMBL19917520 | 0.92 | ESR2 (0.36) | ESR2CYP1A2CYP3A4HSD17B10HPGD | |
| SCHEMBL21546867 | 0.91 | ADRA2C (0.36) | ESR2CYP1A2CYP3A4HSD17B10HPGD | |
| SCHEMBL19917585 | 0.91 | TRPA1 (0.40) | ESR2CYP1A2CYP3A4HSD17B10HPGD | |
| SCHEMBL21414285 | 0.91 | PGR (0.35) | HSD17B10HPGDKDM4EMAPTALDH1A1 | |
| SCHEMBL21414286 | 0.90 | TRPA1 (0.37) | ESR2CYP1A2CYP3A4HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504200-B1 | HETEROCYCLICALLY SUBSTITUTED BIPHENYLS, ESPECIALLY FOR USE IN OPTOELECTRONIC APPARATUSES | CYNORA GMBH (DE) | 2021-01-20 | — | — | EP | disclosed |
| WO-2018037069-A1 | HETEROCYCLICALLY SUBSTITUTED BIPHENYLS, ESPECIALLY FOR USE IN OPTOELECTRONIC APPARATUSES | CYNORA GMBH (DE) | 2018-03-01 | — | — | WO | disclosed |