Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.31 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.31 |
| ▸ | GPR183 | P32249 | 1/20 | 0.31 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17070369 | 0.93 | RARB (0.37) | RARBTHRBTHRAS1PR1S1PR4 | |
| SCHEMBL21985201 | 0.89 | RARB (0.36) | RARBTHRBTHRAALOX5PPARA | |
| SCHEMBL17070375 | 0.88 | RARB (0.36) | RARBTHRBTHRAS1PR1S1PR4 | |
| SCHEMBL17070406 | 0.83 | THRB (0.37) | RARBTHRBTHRAS1PR1S1PR4 | |
| SCHEMBL21787294 | 0.82 | RARB (0.38) | RARBTHRBTHRAS1PR1S1PR4 | |
| SCHEMBL17063582 | 0.82 | THRB (0.40) | RARBTHRBTHRAALOX5PPARA | |
| SCHEMBL31746989 | 0.82 | THRB (0.40) | RARBTHRBTHRAALOX5PPARA | |
| SCHEMBL17070373 | 0.81 | RARB (0.40) | RARBTHRBTHRAALOX5PPARA | |
| SCHEMBL17070377 | 0.81 | RARB (0.36) | RARBTHRBTHRAS1PR1S1PR4 | |
| SCHEMBL17070385 | 0.80 | RARB (0.37) | RARBTHRBTHRAALOX5PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10513657-B2 | Liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2019-12-24 | — | — | US | disclosed |
| US-20180057743-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-03-01 | — | — | US | disclosed |