Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | RARA | P10276 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17070373 | 0.92 | RARB (0.40) | RARBTHRBTHRAPPARAALOX5 | |
| SCHEMBL19917698 | 0.89 | RARB (0.33) | RARBTHRBTHRAPPARAALOX5 | |
| SCHEMBL31746989 | 0.87 | THRB (0.40) | RARBTHRBTHRAPPARAALOX5 | |
| SCHEMBL17063582 | 0.87 | THRB (0.40) | RARBTHRBTHRAPPARAALOX5 | |
| SCHEMBL17070371 | 0.84 | RARB (0.37) | RARBTHRBTHRAPPARAALOX5 | |
| SCHEMBL22173814 | 0.84 | RARB (0.38) | RARBTHRBTHRAALOX5RARA | |
| SCHEMBL17070365 | 0.83 | THRB (0.42) | RARBTHRBTHRAPPARARARA | |
| SCHEMBL17070385 | 0.83 | RARB (0.37) | RARBTHRBTHRAPPARAALOX5 | |
| SCHEMBL17070375 | 0.82 | RARB (0.36) | RARBTHRBTHRARARAMEN1 | |
| SCHEMBL17070470 | 0.82 | THRB (0.40) | RARBTHRBTHRAPPARAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2918658-B1 | Liquid crystalline media with homeotropic alignment | MERCK PATENT GMBH (DE) | 2020-05-13 | — | — | EP | disclosed |