SCHEMBL19917830

SCHEMBL19917830

CC(C)(C)CCCCCCCCOP(=O)(O)O

nearest known ligand 0.61

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 11/20 0.61
LPAR2 Q9HBW0 7/20 0.61
LPAR1 Q92633 6/20 0.61
SMPD1 P17405 3/20 0.40
LPAR5 Q9H1C0 1/20 0.39
S1PR4 O95977 2/20 0.37
S1PR1 P21453 2/20 0.37
S1PR3 Q99500 2/20 0.37
S1PR5 Q9H228 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9437046 1.00 LPAR3 (0.61) LPAR3LPAR2LPAR1SMPD1LPAR5
SCHEMBL19917793 1.00 LPAR3 (0.61) LPAR3LPAR2LPAR1SMPD1LPAR5
SCHEMBL12341207 0.91 LPAR3 (0.54) LPAR3LPAR2LPAR1SMPD1LPAR5
SCHEMBL9437039 0.88 LPAR3 (0.45) LPAR3LPAR2LPAR1SMPD1
SCHEMBL13322581 0.87 LPAR3 (0.47) LPAR3LPAR2LPAR1SMPD1LPAR5
Trolamine SCHEMBL10438012 0.87 LPAR3 (0.47) LPAR3LPAR2LPAR1SMPD1LPAR5
SCHEMBL10438013 0.87 LPAR3 (0.47) LPAR3LPAR2LPAR1SMPD1LPAR5
SCHEMBL7735902 0.85 LPAR3 (0.64) LPAR3LPAR2LPAR1SMPD1LPAR5
SCHEMBL7733418 0.85 LPAR3 (0.64) LPAR3LPAR2LPAR1SMPD1LPAR5
SCHEMBL19509501 0.82 LPAR3 (0.46) LPAR3LPAR2LPAR1SMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210317521-A1 TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION Roche Sequencing Solutions, Inc. (US) 2021-10-14 US disclosed
US-11008613-B2 Tagged nucleotides useful for nanopore detection Roche Sequencing Solutions, Inc. (US) 2021-05-18 US disclosed
US-20200216894-A1 TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION Roche Sequencing Solutions, Inc. (US) 2020-07-09 US disclosed
US-10669580-B2 Tagged nucleotides useful for nanopore detection Roche Sequencing Solutions, Inc. (US) 2020-06-02 US disclosed
US-20180057870-A1 TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION Roche Sequencing Solutions, Inc. 2018-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10669580-B2 Tagged nucleotides useful for nanopore detection PHAX, POLRMT, POLN LPAR3 3474/4885LPAR2 3499/4885LPAR1 3376/4885
US-20180057870-A1 TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION PHAX, POLRMT, POLN LPAR3 3474/4885LPAR2 3499/4885LPAR1 3376/4885
US-20200216894-A1 TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION PHAX, POLRMT, POLN LPAR3 3474/4885LPAR2 3499/4885LPAR1 3376/4885
US-20210317521-A1 TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION PHAX, POLRMT, POLN LPAR3 3474/4885LPAR2 3499/4885LPAR1 3376/4885
US-11008613-B2 Tagged nucleotides useful for nanopore detection PHAX, POLRMT, POLN LPAR3 3474/4885LPAR2 3499/4885LPAR1 3376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.