Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | TPI1 | P60174 | 2/20 | 0.33 |
| ▸ | MVD | P53602 | 1/20 | 0.33 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PGK2 | P07205 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12341207 | 0.86 | LPAR3 (0.54) | LPAR3LPAR2LPAR1SMPD1 | |
| SCHEMBL25472055 | 0.83 | SAT1 (0.41) | LPAR3LPAR2LPAR1GRM4 | |
| SCHEMBL9437046 | 0.82 | LPAR3 (0.61) | LPAR3LPAR2LPAR1SMPD1 | |
| SCHEMBL19917793 | 0.82 | LPAR3 (0.61) | LPAR3LPAR2LPAR1SMPD1 | |
| SCHEMBL19917830 | 0.82 | LPAR3 (0.61) | LPAR3LPAR2LPAR1SMPD1 | |
| SCHEMBL18501124 | 0.81 | GRM4 (0.52) | LPAR3LPAR2LPAR1GRM4TPI1 | |
| SCHEMBL11605559 | 0.79 | LPAR3 (0.47) | LPAR3LPAR2LPAR1TPI1SMPD1 | |
| SCHEMBL9943661 | 0.79 | LPAR3 (0.42) | LPAR3LPAR2LPAR1GRM4TPI1 | |
| SCHEMBL19449056 | 0.78 | MVD (0.36) | GRM4MVDBTN3A1 | |
| SCHEMBL21407715 | 0.78 | LPAR3 (0.41) | LPAR3LPAR2LPAR1GRM4TPI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11701371-B2 | ENPP1 inhibitors and their use for the treatment of cancer | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-07-18 | — | — | US | disclosed |
| US-20210317521-A1 | TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION | Roche Sequencing Solutions, Inc. (US) | 2021-10-14 | — | — | US | disclosed |
| US-11008613-B2 | Tagged nucleotides useful for nanopore detection | Roche Sequencing Solutions, Inc. (US) | 2021-05-18 | — | — | US | disclosed |
| US-20200216894-A1 | TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION | Roche Sequencing Solutions, Inc. (US) | 2020-07-09 | — | — | US | disclosed |
| US-10669580-B2 | Tagged nucleotides useful for nanopore detection | Roche Sequencing Solutions, Inc. (US) | 2020-06-02 | — | — | US | disclosed |
| US-20180057870-A1 | TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION | Roche Sequencing Solutions, Inc. | 2018-03-01 | — | — | US | disclosed |
| WO-2017184871-A1 | CARBIDOPA AND L-DOPA PRODRUGS AND METHODS OF USE | ABBVIE INC. (US) | 2017-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11701371-B2 | ENPP1 inhibitors and their use for the treatment of cancer | ENPP1, ENPP3, ENTPD1 | LPAR3 2478/4885LPAR2 1753/4885LPAR1 1185/4885 |
| US-10669580-B2 | Tagged nucleotides useful for nanopore detection | PHAX, POLRMT, POLN | LPAR3 3474/4885LPAR2 3499/4885LPAR1 3376/4885 |
| US-20180057870-A1 | TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION | PHAX, POLRMT, POLN | LPAR3 3474/4885LPAR2 3499/4885LPAR1 3376/4885 |
| US-20200216894-A1 | TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION | PHAX, POLRMT, POLN | LPAR3 3474/4885LPAR2 3499/4885LPAR1 3376/4885 |
| US-20210317521-A1 | TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION | PHAX, POLRMT, POLN | LPAR3 3474/4885LPAR2 3499/4885LPAR1 3376/4885 |
| US-11008613-B2 | Tagged nucleotides useful for nanopore detection | PHAX, POLRMT, POLN | LPAR3 3474/4885LPAR2 3499/4885LPAR1 3376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.