Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9413470 | 0.80 | KDM4E (0.74) | KDM4ERAB9ANPC1HSD17B10SMN1; SMN2 | |
| SCHEMBL22540503 | 0.78 | BCL2 (0.53) | KDM4ERAB9ANPC1HSD17B10SMN1; SMN2 | |
| SCHEMBL29554156 | 0.77 | KDM4E (0.51) | KDM4ERAB9ANPC1HSD17B10SMN1; SMN2 | |
| SCHEMBL16329999 | 0.76 | KDM4E (0.56) | KDM4ERAB9ANPC1HSD17B10SMN1; SMN2 | |
| SCHEMBL5801394 | 0.75 | KDM4E (1.00) | KDM4ERAB9ANPC1HSD17B10SMN1; SMN2 | |
| SCHEMBL19917788 | 0.74 | BCL2 (0.54) | KDM4ERAB9ANPC1HSD17B10SMN1; SMN2 | |
| SCHEMBL20798560 | 0.74 | HSP90AA1 (0.35) | KDM4ERAB9ANPC1HSD17B10SMN1; SMN2 | |
| SCHEMBL16329998 | 0.73 | SMN1; SMN2 (0.56) | KDM4ERAB9ANPC1HSD17B10SMN1; SMN2 | |
| SCHEMBL19917844 | 0.72 | NPC1 (0.51) | KDM4ERAB9ANPC1HSD17B10SMN1; SMN2 | |
| SCHEMBL22334779 | 0.72 | KDM4E (0.40) | KDM4ERAB9ANPC1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718395-B1 | Novel illumination device comprising a colour converter | BASF SE (DE) | 2018-02-28 | — | — | EP | disclosed |