Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | HPGD | P15428 | 8/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19917859 | 0.77 | KDM4E (0.58) | KDM4ERAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL29553308 | 0.76 | KDM4E (0.42) | KDM4ERAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL5801394 | 0.69 | KDM4E (1.00) | KDM4ERAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL17690385 | 0.68 | ESR1 (0.49) | KDM4ERAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL15803041 | 0.67 | RECQL (0.45) | KDM4ERAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL20954100 | 0.67 | ESR1 (0.44) | KDM4ERAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL12114882 | 0.67 | RECQL (0.47) | KDM4ERAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL29554009 | 0.67 | MAPT (0.53) | KDM4ERAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL15803043 | 0.67 | ESR1 (0.47) | KDM4ERAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL13133843 | 0.66 | ESR1 (0.60) | KDM4ERAB9ANPC1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112457313-B | Naphthalimide-azacyclo-luminescent material and application thereof | 深圳大学 | 2022-04-08 | — | — | CN | disclosed |