Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 1.00 |
| ▸ | RAB9A | P51151 | 8/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 1.00 |
| ▸ | NPC1 | O15118 | 6/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 1.00 |
| ▸ | TP53 | P04637 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | PKM | P14618 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perchlorate SCHEMBL5797378 | 0.91 | KDM4E (0.82) | KDM4ERAB9AHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL9413470 | 0.85 | KDM4E (0.74) | KDM4ERAB9AHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL29802287 | 0.83 | KDM4E (0.71) | KDM4ERAB9AHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL22955317 | 0.81 | NPC1 (0.68) | KDM4ERAB9AHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL29824916 | 0.81 | NPC1 (0.68) | KDM4ERAB9AHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL20740186 | 0.78 | KDM4E (1.00) | KDM4ERAB9AHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL30436694 | 0.77 | RAB9A (0.64) | KDM4ERAB9AHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL14266173 | 0.77 | RAB9A (0.62) | KDM4ERAB9AHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL19917859 | 0.75 | KDM4E (0.58) | KDM4ERAB9AHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL16329999 | 0.73 | KDM4E (0.56) | KDM4ERAB9AHSD17B10NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116919953-A | Application of benzimidazole amine derivative in preparation of antitumor pharmaceutical composition | 广西科技大学 | 2023-10-24 | — | — | CN | claimed |
| CN-116919953-B | Application of benzimidazole amine derivative in preparation of antitumor pharmaceutical composition | 广西科技大学 | 2025-12-05 | — | — | CN | disclosed |
| EP-4370520-A4 | TWO DIMENSIONAL BENZO[4,5]IMIDAZO[2,1-A]ISOINDOLE INCORPORATED NON-FULLERENE ELECTRON ACCEPTORS FOR ORGANIC PHOTOVOLTAIC DEVICES | NAT RES COUNCIL CANADA (CA) | 2025-07-23 | — | — | EP | disclosed |
| EP-4370520-A1 | TWO DIMENSIONAL BENZO[4,5]IMIDAZO[2,1-A]ISOINDOLE INCORPORATED NON-FULLERENE ELECTRON ACCEPTORS FOR ORGANIC PHOTOVOLTAIC DEVICES | National Research Council of Canada (CA) | 2024-05-22 | — | — | EP | disclosed |
| EP-4370520-A1 | TWO DIMENSIONAL BENZO[4,5]IMIDAZO[2,1-A]ISOINDOLE INCORPORATED NON-FULLERENE ELECTRON ACCEPTORS FOR ORGANIC PHOTOVOLTAIC DEVICES | National Research Council of Canada (CA) | 2024-05-22 | — | — | EP | disclosed |
| CN-116919953-A | Application of benzimidazole amine derivative in preparation of antitumor pharmaceutical composition | 广西科技大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-116919953-A | Application of benzimidazole amine derivative in preparation of antitumor pharmaceutical composition | 广西科技大学 | 2023-10-24 | — | — | CN | disclosed |
| WO-2023283728-A1 | TWO DIMENSIONAL BENZO[4,5]IMIDAZO[2,1-A]ISOINDOLE INCORPORATED NON-FULLERENE ELECTRON ACCEPTORS FOR ORGANIC PHOTOVOLTAIC DEVICES | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023283728-A1 | TWO DIMENSIONAL BENZO[4,5]IMIDAZO[2,1-A]ISOINDOLE INCORPORATED NON-FULLERENE ELECTRON ACCEPTORS FOR ORGANIC PHOTOVOLTAIC DEVICES | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2023-01-19 | — | — | WO | disclosed |
| US-8420052-B2 | Imaging agents useful for identifying AD pathology | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2013-04-16 | — | — | US | disclosed |
| US-8420052-B2 | Imaging agents useful for identifying AD pathology | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2013-04-16 | — | — | US | disclosed |
| US-20100098634-A1 | Imaging Agents Useful for Identifying AD Pathology | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2010-04-22 | — | — | US | disclosed |
| US-20100098634-A1 | Imaging Agents Useful for Identifying AD Pathology | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2010-04-22 | — | — | US | disclosed |
| WO-2010011964-A2 | IMAGING AGENTS USEFUL FOR IDENTIFYING AD PATHOLOGY | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2010-01-28 | — | — | WO | disclosed |
| WO-2006030127-A1 | COMPOSITION COMPRISING AT LEAST ONE SUBSTITUTED CARBOCYANINE DERIVATIVE, KERATIN FIBRE TREATMENT METHOD USING SAME, ASSOCIATED DEVICE AND USE THEREOF | L'OREAL (FR) | 2006-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100098634-A1 | Imaging Agents Useful for Identifying AD Pathology | APP, APBA1, PYGB | KDM4E 2997/4885RAB9A 3454/4885HSD17B10 3219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.