SCHEMBL19918549

SCHEMBL19918549

c1ccc(-n2c3ccc(-c4ccc5sc6ccccc6c5c4)cc3c3c4cccc5c4c(cc32)-c2ccccc2-5)cc1

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ATM Q13315 1/20 0.35
ALOX5 P09917 1/20 0.33
HSD17B10 Q99714 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP1 P29466 1/20 0.32
HIF1A Q16665 1/20 0.32
GPR3 P46089 1/20 0.32
PIM3 Q86V86 1/20 0.31
JAK2 O60674 1/20 0.31
JAK3 P52333 1/20 0.31
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19918552 0.96 PIM3 (0.34) L3MBTL1KDM4EATMALOX5HSD17B10
SCHEMBL19918550 0.95 PIM3 (0.36) L3MBTL1KDM4EATMALOX5HSD17B10
SCHEMBL19918557 0.95 PIM3 (0.36) L3MBTL1KDM4EATMALOX5HSD17B10
SCHEMBL19918551 0.95 PIM3 (0.34) L3MBTL1KDM4EATMALOX5HSD17B10
SCHEMBL19918501 0.94 L3MBTL1 (0.34) L3MBTL1KDM4EATMALOX5HSD17B10
SCHEMBL19918629 0.94 KDM4E (0.36) L3MBTL1KDM4EATMALOX5
SCHEMBL19918497 0.94 KDM4E (0.36) L3MBTL1KDM4EATMALOX5
SCHEMBL19918647 0.94 KDM4E (0.36) L3MBTL1KDM4EATMALOX5
SCHEMBL19918553 0.94 PIM3 (0.35) ATMALOX5ALDH1A1PIM3
SCHEMBL19918495 0.93 ALOX5 (0.33) L3MBTL1ALOX5HSD17B10ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018038400-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING SAME 주식회사 두산 2018-03-01 WO disclosed