SCHEMBL19918609

SCHEMBL19918609

c1ccc(-c2nc(-c3ccc4oc5ccccc5c4c3)nc(-n3c4ccc(-c5ccc6oc7ccccc7c6c5)cc4c4c5cccc6c5c(cc43)-c3ccccc3-6)n2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.33
PLA2G4A P47712 3/20 0.33
PLA2G10 O15496 1/20 0.33
CHEK2 O96017 1/20 0.32
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31
ALDH1A1 P00352 3/20 0.31
HPGD P15428 3/20 0.31
TSHR P16473 2/20 0.31
MAPK1 P28482 1/20 0.31
CASP1 P29466 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TERT O14746 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19918598 1.00 PLA2G2A (0.33) PLA2G2APLA2G4APLA2G10CHEK2HSP90AA1
SCHEMBL19918601 0.99 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10CHEK2HSP90AA1
SCHEMBL19918606 0.97 PLA2G2A (0.32) PLA2G2APLA2G4APLA2G10CHEK2HSP90AA1
SCHEMBL19918602 0.93 PLA2G2A (0.33) PLA2G2APLA2G4APLA2G10CHEK2HSP90AA1
SCHEMBL19918604 0.92 PLA2G2A (0.32) PLA2G2APLA2G4APLA2G10CHEK2HSP90AA1
SCHEMBL19918597 0.92 PLA2G2A (0.32) PLA2G2APLA2G4APLA2G10CHEK2HSP90AA1
SCHEMBL19918536 0.92 ALDH1A1 (0.32) CHEK2HSP90AA1HSP90AB1ALDH1A1HPGD
SCHEMBL19918447 0.92
SCHEMBL19918603 0.91 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10CHEK2HSP90AA1
SCHEMBL19918596 0.91 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10CHEK2HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018038400-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING SAME 주식회사 두산 2018-03-01 WO disclosed