Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31647297 | 0.81 | ALDH1A1 (0.51) | HSD17B10ALDH1A1KDM4EKMT2ARXFP1 | |
| SCHEMBL1991573 | 0.79 | KDM4E (0.51) | HSD17B10ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL1989725 | 0.78 | ALDH1A1 (0.46) | HSD17B10ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL2031142 | 0.77 | HRH4 (0.54) | ALDH1A1KMT2AMEN1ELANEMAPT | |
| SCHEMBL6499160 | 0.74 | HSD17B10 (0.44) | HSD17B10ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL1993219 | 0.74 | KDM4E (0.49) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1990509 | 0.73 | LATS1 (0.42) | HSD17B10ALDH1A1KDM4ESMN1; SMN2RECQL | |
| SCHEMBL1993736 | 0.72 | ALDH1A1 (0.48) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1997280 | 0.71 | ELANE (0.44) | ALDH1A1KDM4EELANETDP1 | |
| SCHEMBL29777989 | 0.71 | ELANE (0.44) | ALDH1A1KDM4EELANETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | HSD17B10 2995/4885ALDH1A1 297/4885KDM4E 3351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.