⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23940491 | 0.89 | — | — | |
| SCHEMBL15717402 | 0.82 | — | — | |
| SCHEMBL19900597 | 0.82 | CA1 (0.32) | — | |
| SCHEMBL19900599 | 0.82 | CA1 (0.32) | — | |
| SCHEMBL419355 | 0.82 | MMP1 (0.38) | — | |
| SCHEMBL854380 | 0.82 | MMP1 (0.38) | — | |
| SCHEMBL3050186 | 0.82 | MMP1 (0.38) | — | |
| SCHEMBL25176906 | 0.79 | APLNR (0.31) | — | |
| SCHEMBL8221420 | 0.79 | APLNR (0.31) | — | |
| SCHEMBL15717701 | 0.79 | APLNR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11673869-B2 | 4-oxazolidinone antimicrobial agents | NORTH CAROLINA STATE UNIVERSITY (US) | 2023-06-13 | — | — | US | disclosed |
| US-11673869-B2 | 4-oxazolidinone antimicrobial agents | NORTH CAROLINA STATE UNIVERSITY (US) | 2023-06-13 | — | — | US | disclosed |
| US-20210323934-A1 | 4-OXAZOLIDINONE ANTIMICROBIAL AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-10-21 | — | — | US | disclosed |
| US-10844025-B2 | 4-oxazolidinone antimicrobial agents | NORTH CAROLINA STATE UNIVERSITY (US) | 2020-11-24 | — | — | US | disclosed |
| US-20190177285-A1 | 4-OXAZOLIDINONE ANTIMICROBIAL AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-06-13 | — | — | US | disclosed |
| WO-2018039242-A1 | 4-OXAZOLIDINONE ANTIMICROBIAL AGENTS | NORTH CAROLINA STATE UNIVERSITY (US) | 2018-03-01 | — | — | WO | disclosed |