SCHEMBL199242

SCHEMBL199242

CCCCCCCCCCC[CH]SC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
THRB P10828 1/20 0.44
FAAH O00519 2/20 0.42
TRPV1 Q8NER1 1/20 0.42
DNM1 Q05193 3/20 0.41
EP300 Q09472 1/20 0.38
GMNN O75496 1/20 0.37
USP2 O75604 1/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
CYP2C9 P11712 1/20 0.37
ALOX15 P16050 1/20 0.37
APEX1 P27695 1/20 0.37
CYP2C19 P33261 1/20 0.37
RECQL P46063 1/20 0.37
BLM P54132 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5073215 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL200469 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL200480 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL198829 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL198939 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL198695 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL200934 1.00
SCHEMBL387241 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL199322 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL200492 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9758502-B2 Dihydropyrone compounds and herbicides comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-09-12 US disclosed
CN-104797567-B Dihydropyrone compound and herbicide containing the same 住友化学株式会社 2017-06-20 CN disclosed
EP-2925736-B1 DIHYDROPYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME SUMITOMO CHEMICAL CO (JP) 2017-01-04 EP disclosed
US-20150299156-A1 DIHYDROPYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-22 US disclosed
EP-2925736-A1 DIHYDROPYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME Sumitomo Chemical Co., Ltd (JP) 2015-10-07 EP disclosed
WO-2014084407-A1 DIHYDROPYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-06-05 WO disclosed
US-8481736-B2 Liquid crystalline rylene tetracarboxylic acid derivatives and use thereof BASF SE (DE) 2013-07-09 US disclosed
US-8088922-B2 Dibenzorylenetetracarboximides as infrared absorbers BASF AKTIENGESELLSCHAFT (DE) 2012-01-03 US disclosed
EP-2029573-B1 DIBENZORYLENETETRACARBOXIMIDES AS INFRARED ABSORBERS BASF SE (DE) 2011-10-26 EP disclosed
US-20110042651-A1 LIQUID CRYSTALLINE RYLENE TETRACARBOXYLIC ACID DERIVATIVES AND USE THEREOF BASF SE (DE) 2011-02-24 US disclosed
US-4482655-A SUBSTITUTED SUCCINIC ANHYDRIDE COUPLER MILLIKEN RESEARCH CORPORATION (US) 1984-11-13 US disclosed
US-4328041-A TREATED WITH SUBSTITUTED SUCCINIC ANHYDRIDE MILLIKEN RESEARCH CORPORATION (US) 1982-05-04 US disclosed
US-4192792-A Atactic polypropylene KENRICH PETROCHEMICALS, INC. (US) 1980-03-11 US disclosed
EP-0007748-A1 Composition containing atactic polypropylene and a filler treated with an organo-titanate chelate KENRICH PETROCHEMICALS, INC. (US) 1980-02-06 EP disclosed
US-4122062-A FILLERS KENRICH PETROCHEMICALS, INC. (US) 1978-10-24 US disclosed
US-4098758-A ORGANIC ACIDS, FOR USE IN POLYMER SYSTEMS KENRICH PETROCHEMICALS, INC. (US) 1978-07-04 US disclosed
US-4096110-A Filled polyesters containing organic titanate esters KENRICH PETROCHEMICALS, INC. (US) 1978-06-20 US disclosed
US-4094853-A Alkoxy titanate salts useful as coupling agents KENRICH PETROCHEMICALS, INC. (US) 1978-06-13 US disclosed
US-4087402-A USED FOR TREATMENT OF INORGANIC FILLERS KENRICH PETROCHEMICALS, INC. (US) 1978-05-02 US disclosed
US-4069192-A ORGANIC KENRICH PETROCHEMICALS, INC. (US) 1978-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150299156-A1 DIHYDROPYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME CBR3, DDT, WEE2 TSHR 3931/4885THRB 3938/4885FAAH 3369/4885
US-20110042651-A1 LIQUID CRYSTALLINE RYLENE TETRACARBOXYLIC ACID DERIVATIVES AND USE THEREOF TPR, ROR1, CA3 TSHR 1618/4885THRB 2991/4885FAAH 3869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.