Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18411736 | 0.91 | L3MBTL1 (0.33) | L3MBTL1TRPA1TRPM8EPHX1 | |
| SCHEMBL18611198 | 0.90 | — | — | |
| SCHEMBL7363310 | 0.90 | — | — | |
| SCHEMBL685314 | 0.90 | — | — | |
| SCHEMBL18611197 | 0.90 | — | — | |
| SCHEMBL18752288 | 0.87 | CYP2C9 (0.32) | — | |
| SCHEMBL27844011 | 0.87 | — | — | |
| SCHEMBL8604797 | 0.85 | — | — | |
| SCHEMBL24649615 | 0.81 | — | — | |
| SCHEMBL4394617 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018039518-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-03-01 | — | — | WO | disclosed |