⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13799410 | 0.96 | — | — | |
| SCHEMBL24649615 | 0.96 | — | — | |
| SCHEMBL4394617 | 0.96 | — | — | |
| SCHEMBL19924461 | 0.85 | L3MBTL1 (0.38) | — | |
| SCHEMBL7044994 | 0.82 | — | — | |
| SCHEMBL18752288 | 0.79 | CYP2C9 (0.32) | — | |
| SCHEMBL22186493 | 0.79 | — | — | |
| SCHEMBL18411736 | 0.77 | L3MBTL1 (0.33) | — | |
| SCHEMBL20076697 | 0.76 | — | — | |
| SCHEMBL764723 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215775-A1 | PYRIDONE COMPOUNDS AS TRPA1 INHIBITORS | D. E. SHAW RESEARCH, LLC (US) | 2023-11-09 | — | — | WO | disclosed |
| WO-2023150591-A2 | PYRIDAZINONE COMPOUNDS AS TRPA1 INHIBITORS | D.E. SHAW RESEARCH, LLC (US) | 2023-08-10 | — | — | WO | disclosed |
| WO-2023150592-A2 | N3-SUBSTITUTED URACIL COMPOUNDS AS TRPA1 INHIBITORS | D.E. SHAW RESEARCH, LLC (US) | 2023-08-10 | — | — | WO | disclosed |
| EP-3894402-B1 | N-CONTAINING CHROMEN-4-ONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2023-07-05 | — | — | EP | disclosed |
| US-10292972-B1 | Pharmaceutical composition for treating cancer and a method thereof | KING ABDULAZIZ UNIVERSITY (SA) | 2019-05-21 | — | — | US | disclosed |
| US-20190125732-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING CANCER AND A METHOD THEREOF | KING ABDULAZIZ UNIVERSITY (SA) | 2019-05-02 | — | — | US | disclosed |
| US-9802952-B2 | Method and apparatus for the synthesis of dihydroartemisinin and artemisinin derivatives | Max-Plank-Gesellschaft zur Förderung der Wissenschaften e.v. (DE) | 2017-10-31 | — | — | US | disclosed |
| US-9802952-B2 | Method and apparatus for the synthesis of dihydroartemisinin and artemisinin derivatives | Max-Plank-Gesellschaft zur Förderung der Wissenschaften e.v. (DE) | 2017-10-31 | — | — | US | disclosed |
| EP-3022208-B1 | METHOD AND APPARATUS FOR THE SYNTHESIS OF DIHYDROARTEMISININ AND ARTEMISININ DERIVATIVES | MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS (DE) | 2017-06-14 | — | — | EP | disclosed |
| US-9567345-B2 | Pharmaceutically active pyrazolo-triazine derivatives | LEAD DISCOVERY CENTER GMBH (DE) | 2017-02-14 | — | — | US | disclosed |
| EP-2229956-A1 | Multimeric constructs | Genzyme Corporation (US) | 2010-09-22 | — | — | EP | disclosed |
| US-5854407-A | 15-hydroxy 6,9-hemiacetal erythromycin compounds | TAKEDA CHEMICAL CORPORATION (JP) | 1998-12-29 | — | — | US | disclosed |
| EP-0561413-B1 | Erythromycin deriatives, preparation and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-06-05 | — | — | EP | disclosed |
| US-5470961-A | 14 and/or 15-hydroxy 6,9 hemiacetal erythromycin derivatives | TAKEDA CHEMICAL IND., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0561413-A1 | Erythromycin deriatives, preparation and use thereof | Takeda Chemical Industries, Ltd. (JP) | 1993-09-22 | — | — | EP | disclosed |
| US-5175150-A | Stimulating digective contraction | KITASATO, KENKYUSHO (JP) | 1992-12-29 | — | — | US | disclosed |
| US-5008249-A | Administering anhydroerythromycin derivative | KITASATO KENKYUSHO (JP) | 1991-04-16 | — | — | US | disclosed |
| US-4948782-A | A method of promoting the growth of domestic animals with erythromycin derivative containing composition | KITASATO KENKYUSHO (JP) | 1990-08-14 | — | — | US | disclosed |
| EP-0215355-A2 | Erythromycin derivative and process for preparing the same | KITASATO KENKYUSHO (JP) | 1987-03-25 | — | — | EP | disclosed |
| EP-0213617-A2 | Digestive tract contractile motion stimulant | KITASATO KENKYUSHO (JP) | 1987-03-11 | — | — | EP | disclosed |