SCHEMBL19925262

SCHEMBL19925262

CCCCCCCC(=O)Oc1ccc(C[O])cc1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
ALOX15 P16050 1/20 0.50
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
THRB P10828 2/20 0.49
THRA P10827 1/20 0.49
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
HTT P42858 1/20 0.47
HSD17B10 Q99714 1/20 0.47
ESR1 P03372 1/20 0.46
CA2 P00918 2/20 0.45
BCL9 O00512 1/20 0.45
CTNNB1 P35222 1/20 0.45
DGKA P23743 1/20 0.44
HTR1A P08908 1/20 0.44
HTR1B P28222 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5696798 0.90 KMT2A (0.68) KMT2ASMN1; SMN2ALOX15NPC1RAB9A
SCHEMBL15549028 0.90 KMT2A (0.68) KMT2ASMN1; SMN2ALOX15NPC1RAB9A
SCHEMBL38661498 0.90 KMT2A (0.68) KMT2ASMN1; SMN2ALOX15NPC1RAB9A
SCHEMBL5696854 0.90 KMT2A (0.68) KMT2ASMN1; SMN2ALOX15NPC1RAB9A
SCHEMBL5696715 0.90 KMT2A (0.68) KMT2ASMN1; SMN2ALOX15NPC1RAB9A
SCHEMBL21470145 0.89 KMT2A (0.57) KMT2ASMN1; SMN2ALOX15NPC1RAB9A
SCHEMBL28371002 0.89 KMT2A (0.59) KMT2ASMN1; SMN2ALOX15NPC1RAB9A
SCHEMBL28366896 0.89 KMT2A (0.59) KMT2ASMN1; SMN2ALOX15NPC1RAB9A
SCHEMBL15987877 0.89 KMT2A (0.59) KMT2ASMN1; SMN2ALOX15NPC1RAB9A
SCHEMBL15549194 0.88 KMT2A (0.66) KMT2ASMN1; SMN2ALOX15NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242568-A1 POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES MIRECA MEDICINES GMBH (DE) 2023-08-03 US claimed
US-20210317156-A1 NEW POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES MIRECA MEDICINES GMBH (DE) 2021-10-14 US claimed
EP-3507295-A1 NEW POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES Mireca Medicines GmbH (DE) 2019-07-10 EP claimed
WO-2018041942-A9 NEW POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES MIRECA MEDICINES GMBH (DE) 2019-01-17 WO claimed
WO-2018041942-A1 NEW POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES BIOLOG LIFE SCIENCE INSTITUTE FORSCHUNGSLABOR UND BIOCHEMICA-VERTRIEB GMBH (DE) 2018-03-08 WO claimed
US-20230242568-A1 POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES MIRECA MEDICINES GMBH (DE) 2023-08-03 US disclosed
US-20210317156-A1 NEW POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES MIRECA MEDICINES GMBH (DE) 2021-10-14 US disclosed
EP-3507295-A1 NEW POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES Mireca Medicines GmbH (DE) 2019-07-10 EP disclosed
WO-2018041942-A9 NEW POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES MIRECA MEDICINES GMBH (DE) 2019-01-17 WO disclosed
WO-2018041942-A1 NEW POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES BIOLOG LIFE SCIENCE INSTITUTE FORSCHUNGSLABOR UND BIOCHEMICA-VERTRIEB GMBH (DE) 2018-03-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242568-A1 POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES PRKG1, PRKG2, PRKAG3 KMT2A 2118/4885SMN1; SMN2 4500/4885ALOX15 4759/4885
US-20210317156-A1 NEW POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES PRKG1, PRKG2, PDE7A KMT2A 2369/4885SMN1; SMN2 4506/4885ALOX15 4715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.