SCHEMBL1992795

SCHEMBL1992795

CCCCCCN=C[SiH2]OC(CC)CC

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.34
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1995116 0.70 NAAA (0.32) NAAAMEN1KMT2A
SCHEMBL1992741 0.68 NAAA (0.31) NAAAMEN1KMT2A
SCHEMBL28199568 0.65 TSHR (0.36) MAPT
SCHEMBL5575101 0.65 TSHR (0.36) MAPT
SCHEMBL5573920 0.65 TSHR (0.36) MAPT
SCHEMBL14865444 0.64 TSHR (0.47) NAAAKDM4EALDH1A1CYP1A2MAPT
SCHEMBL14123990 0.62 TSHR (0.44) NAAAKDM4EALDH1A1CYP1A2MAPT
SCHEMBL22672719 0.62 TSHR (0.44) NAAAKDM4EALDH1A1CYP1A2MAPT
SCHEMBL20628593 0.62 TSHR (0.44) NAAAKDM4EALDH1A1CYP1A2MAPT
SCHEMBL10278493 0.62 TSHR (0.44) NAAAKDM4EALDH1A1CYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2803699-B1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME BRIDGESTONE CORP (JP) 2018-09-12 EP disclosed
US-9623705-B2 Method for producing modified conjugated diene polymer/copolymer, modified conjugated diene polymer/copolymer, and rubber composition and tire using the same BRIDGESTONE CORPORATION (JP) 2017-04-18 US disclosed
US-9447208-B2 Rubber composition for tire, vulcanized rubber composition for tire, and tires using same BRIDGESTONE CORPORATION (JP) 2016-09-20 US disclosed
US-20140357804-A1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME BRIDGESTONE CORPORATION (JP) 2014-12-04 US disclosed
EP-2803699-A1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME Bridgestone Corporation (JP) 2014-11-19 EP disclosed
EP-2266819-B1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME BRIDGESTONE CORP (JP) 2013-11-06 EP disclosed
US-20110146877-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed
EP-2266819-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME Bridgestone Corporation (JP) 2010-12-29 EP disclosed