Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19928273 | 0.90 | CYP11B1 (0.46) | GRM5CYP11B1CYP11B2AXLKMT2A | |
| SCHEMBL19928285 | 0.88 | GRM5 (0.51) | GRM5CYP11B1CYP11B2AXLIRAK4 | |
| SCHEMBL19902047 | 0.79 | CYP11B2 (0.51) | GRM5CYP11B1CYP11B2AXLKMT2A | |
| SCHEMBL19928291 | 0.78 | CYP11B2 (0.43) | GRM5CYP11B1CYP11B2AXLKMT2A | |
| SCHEMBL19902102 | 0.78 | GRM5 (0.70) | GRM5AXLIRAK4NOTUMKMT2A | |
| SCHEMBL5220524 | 0.74 | GRM5 (0.68) | GRM5AXLNOTUM | |
| SCHEMBL16202060 | 0.73 | GRM4 (0.52) | KMT2AGRM4NPC1RAB9A | |
| SCHEMBL5216403 | 0.73 | GRM5 (0.74) | GRM5AXLNOTUMCHRNB2CHRNA5 | |
| SCHEMBL24908424 | 0.71 | GRM5 (0.54) | GRM5IRAK4NOTUMKCNJ1 | |
| SCHEMBL7386770 | 0.71 | CLK4 (0.53) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9911928-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2018-03-06 | — | — | US | disclosed |