Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.57 |
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4303776 | 0.79 | EPHX1 (0.62) | EPHX1TRPM8TRPA1ALDH1A1HPGD | |
| SCHEMBL1863411 | 0.78 | EPHX1 (0.60) | EPHX1TRPM8TRPA1ALDH1A1HPGD | |
| SCHEMBL20226808 | 0.78 | EPHX1 (0.60) | EPHX1TRPM8TRPA1ALDH1A1HPGD | |
| SCHEMBL10034576 | 0.77 | EPHX1 (0.75) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL6128506 | 0.77 | EPHX1 (0.75) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL10001728 | 0.77 | EPHX1 (0.75) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL291653 | 0.77 | EPHX1 (0.75) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL12381600 | 0.77 | EPHX1 (0.75) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL2057748 | 0.77 | EPHX1 (0.75) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL28481073 | 0.76 | EPHX1 (0.63) | EPHX1TRPM8TRPA1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9908846-B2 | Composition, synthesis, and use of new arylsulfonyl isonitriles | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) | 2018-03-06 | — | — | US | disclosed |