Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.75 |
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12381600 | 1.00 | EPHX1 (0.75) | EPHX1TRPM8TRPA1TRPV1KCNA5 | |
| SCHEMBL2057748 | 1.00 | EPHX1 (0.75) | EPHX1TRPM8TRPA1TRPV1KCNA5 | |
| SCHEMBL10034576 | 1.00 | EPHX1 (0.75) | EPHX1TRPM8TRPA1TRPV1KCNA5 | |
| SCHEMBL10001728 | 1.00 | EPHX1 (0.75) | EPHX1TRPM8TRPA1TRPV1KCNA5 | |
| SCHEMBL6128506 | 1.00 | EPHX1 (0.75) | EPHX1TRPM8TRPA1TRPV1KCNA5 | |
| SCHEMBL22361298 | 0.89 | EPHX1 (0.72) | EPHX1TRPM8TRPA1TRPV1KCNA5 | |
| Hexane SCHEMBL28846476 | 0.89 | EPHX1 (0.62) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL10001727 | 0.88 | EPHX1 (0.70) | EPHX1TRPM8TRPA1TRPV1KCNA5 | |
| SCHEMBL6128484 | 0.88 | EPHX1 (0.70) | EPHX1TRPM8TRPA1TRPV1KCNA5 | |
| SCHEMBL10034575 | 0.88 | EPHX1 (0.70) | EPHX1TRPM8TRPA1TRPV1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160184-A | Preparation method of N-p-phenylacetonitrile menthane alkyl formamide | 安徽丰乐香料有限责任公司 | 2022-10-11 | — | — | CN | claimed |
| CN-114369037-A | Production process of compound cooling agent | 南通亚香食品科技有限公司 | 2022-04-19 | — | — | CN | claimed |
| CN-112353709-A | Toothpaste compounded with mint freshener | 广州市盛龙口腔清洁用品有限公司 | 2021-02-12 | — | — | CN | claimed |
| CN-104642983-B | One kind compounding coolant agent composition and its preparation technology | 昆山亚香香料股份有限公司 | 2017-06-16 | — | — | CN | claimed |
| CN-104800090-A | Novel cooling agent composition formed by compounding mint amide derivatives | KUNSHAN ASIA AROMA CO LTD | 2015-07-29 | — | — | CN | claimed |
| CN-104642983-A | Compound cooling agent composition and preparation technology thereof | KUNSHAN ASIA AROMA CO LTD | 2015-05-27 | — | — | CN | claimed |
| CN-103420867-A | Synthesis process of novel algefacient ethyl N-[[5-methyl-2-(isopropyl)cyclohexyl]carbonyl]glycinate | ZHEJIANG XINHUA CHEMICAL CO LTD | 2013-12-04 | — | — | CN | claimed |
| CN-102942484-A | Menthyl formates, and preparation method and application thereof | UNIV ZHENGZHOU LIGHT IND | 2013-02-27 | — | — | CN | claimed |
| US-20250288583-A1 | Treatment of Mucus Hypersecretion | ALTA RESEARCH, LLC | 2025-09-18 | — | — | US | disclosed |
| CN-117945886-B | Synthesis method of WS series cooling agent key intermediate menthyl formic acid | 江苏宏邦化工科技有限公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-119039169-A | Preparation method of cooling agent WS-3 | 辽宁友之泰医药科技有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-107949555-B | Physiological cooling compound | 西姆莱斯有限公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-117945886-A | Synthesis method of WS series cooling agent key intermediate menthyl formic acid | 江苏宏邦化工科技有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-115160184-A | Preparation method of N-p-phenylacetonitrile menthane alkyl formamide | 安徽丰乐香料有限责任公司 | 2022-10-11 | — | — | CN | disclosed |
| US-20050084447-A1 | Radioligands for the TRP-M8 receptor and methods therewith | WEI EDWARD T (US) | 2005-04-21 | — | — | US | disclosed |
| US-20050054651-A1 | Compositions and methods for the treatment of disease associated with Trp-p8 expression | DENDREON CORPORATION (US) | 2005-03-10 | — | — | US | disclosed |
| WO-2005020897-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASE ASSOCIATED WITH TRP-P8 EXPRESSION | DENDREON CORPORATION (US) | 2005-03-10 | — | — | WO | disclosed |
| EP-1311158-B1 | COMPOSITION HAVING INSECT REPELLENT CHARACTERISTICS | GIVAUDAN SA (CH) | 2004-08-11 | — | — | EP | disclosed |
| US-20040028714-A1 | Composition having insect repellent characteristics | GIVAUDAN SA (CH) | 2004-02-12 | — | — | US | disclosed |
| US-4033994-A | CARBOXY SUBSTITUTED, COOLING ACTION ON SKIN | WILKINSON SWORD LIMITED (EN) | 1977-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050084447-A1 | Radioligands for the TRP-M8 receptor and methods therewith | TRPM8, GPR68, OPRL1 | EPHX1 4381/4885TRPM8 1/4885TRPA1 7/4885 |
| US-20250288583-A1 | Treatment of Mucus Hypersecretion | TRPM8, GPR18, OPRL1 | EPHX1 771/4885TRPM8 1/4885TRPA1 10/4885 |
| US-20050054651-A1 | Compositions and methods for the treatment of disease associated with Trp-p8 expression | TRPC4, TRPC3, TRPC1 | EPHX1 2270/4885TRPM8 8/4885TRPA1 31/4885 |
| US-20040028714-A1 | Composition having insect repellent characteristics | SUV39H1, PNMT, SUV39H2 | EPHX1 690/4885TRPM8 36/4885TRPA1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.