SCHEMBL19928527

SCHEMBL19928527

CC(C)(C)[Si](C)(C)OC[C@@H](OCc1ccccc1)[C@@H](OCc1ccccc1)[C@H](OCc1ccccc1)[C@H](O)COC[C@@H](OCc1ccccc1)[C@@H](O)[C@H](OCc1ccccc1)[C@@H](CO)OCc1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.31
CA1 P00915 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19928559 0.95 MAPT (0.33) MAPTKMT2ACA1
SCHEMBL19928533 0.92 MAPT (0.33) MAPTCA1
SCHEMBL18591520 0.91 MAPT (0.35) MAPTCA1
SCHEMBL19928534 0.90 MAPT (0.36) MAPTKMT2ACA1
SCHEMBL15892778 0.87 MAPT (0.37) MAPTKMT2ACA1
SCHEMBL19928558 0.86 MAPT (0.35) MAPTKMT2ACA1
SCHEMBL19928535 0.86
SCHEMBL19928526 0.85 MAPT (0.36) MAPTKMT2ACA1
SCHEMBL14747381 0.84 CA1 (0.41) MAPTKMT2ACA1
SCHEMBL15892776 0.81 MAPT (0.33) MAPTCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9907854-B2 Crosslinking reagents, macromolecules, therapeutic bioconjugates, and synthetic methods thereof CellMosaic, Inc. (US) 2018-03-06 US disclosed