Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19928534 | 0.87 | MAPT (0.36) | CA1KMT2ACA2CA7CA9 | |
| SCHEMBL19928526 | 0.86 | MAPT (0.36) | CA1KMT2ACA2CA7CA9 | |
| SCHEMBL5962118 | 0.86 | KMT2A (0.39) | CA1KMT2ACA2CA7CA9 | |
| SCHEMBL19928558 | 0.86 | MAPT (0.35) | CA1KMT2ACA2CA7CA9 | |
| SCHEMBL19928559 | 0.85 | MAPT (0.33) | CA1KMT2ACYP2C19MAPT | |
| SCHEMBL21727779 | 0.85 | MAPT (0.34) | CA1KMT2ACA2CA7CA9 | |
| SCHEMBL19928527 | 0.84 | MAPT (0.32) | CA1KMT2AMAPT | |
| SCHEMBL15892778 | 0.84 | MAPT (0.37) | CA1KMT2ACA2CA7CA9 | |
| SCHEMBL18591520 | 0.83 | MAPT (0.35) | CA1CA2CA7CA9CYP2C19 | |
| SCHEMBL14747384 | 0.83 | MAPT (0.35) | CA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389565-B2 | Antidiabetic agents; controlling carbohydrate metabolism | SIMON FRASER UNIVERSITY (CA) | 2013-03-05 | — | — | US | disclosed |