Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19928533 | 0.97 | MAPT (0.33) | MAPTCA1CYP2C19BTN3A1 | |
| SCHEMBL19928527 | 0.95 | MAPT (0.32) | MAPTKMT2ACA1 | |
| SCHEMBL19928534 | 0.93 | MAPT (0.36) | MAPTKMT2ACA1CYP2C19BTN3A1 | |
| SCHEMBL18591520 | 0.90 | MAPT (0.35) | MAPTCA1CYP2C19BTN3A1 | |
| SCHEMBL19928558 | 0.87 | MAPT (0.35) | MAPTKMT2ACA1CYP2C19BTN3A1 | |
| SCHEMBL15892778 | 0.86 | MAPT (0.37) | MAPTKMT2ACA1CYP2C19BTN3A1 | |
| SCHEMBL19928526 | 0.86 | MAPT (0.36) | MAPTKMT2ACA1CYP2C19BTN3A1 | |
| SCHEMBL14747381 | 0.85 | CA1 (0.41) | MAPTKMT2ACA1CYP2C19 | |
| SCHEMBL19928535 | 0.84 | — | — | |
| SCHEMBL15892776 | 0.82 | MAPT (0.33) | MAPTCA1CYP2C19BTN3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9907854-B2 | Crosslinking reagents, macromolecules, therapeutic bioconjugates, and synthetic methods thereof | CellMosaic, Inc. (US) | 2018-03-06 | — | — | US | disclosed |