Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12581441 | 0.88 | MEN1 (0.32) | MEN1KMT2ADNM1KDM4AHIF1A | |
| SCHEMBL12347474 | 0.88 | MEN1 (0.32) | MEN1KMT2ADNM1KDM4AHIF1A | |
| SCHEMBL260576 | 0.88 | MEN1 (0.32) | MEN1KMT2ADNM1KDM4AHIF1A | |
| SCHEMBL18372007 | 0.88 | MEN1 (0.33) | MEN1KMT2ADNM1 | |
| SCHEMBL26549795 | 0.88 | MEN1 (0.33) | MEN1KMT2ADNM1 | |
| SCHEMBL2603166 | 0.88 | KMT2A (0.33) | MEN1KMT2ADNM1 | |
| SCHEMBL19601268 | 0.87 | — | — | |
| SCHEMBL23394798 | 0.82 | — | — | |
| SCHEMBL14473178 | 0.82 | — | — | |
| SCHEMBL14073678 | 0.80 | PRMT3 (0.32) | KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180066258-A1 | SPECIFIC SYNTHETIC CHIMERIC XENONUCLEIC ACID GUIDE RNA; s(XNA-gRNA) FOR ENHANCING CRISPR MEDIATED GENOME EDITING EFFICIENCY | POWELL MICHAEL J (US) | 2018-03-08 | — | — | US | disclosed |