SCHEMBL260576

SCHEMBL260576

CCC(=O)N(CCNC(=O)CN(CCNC(=O)CN(CCNC(=O)CN(CCN)C(=O)CC)C(=O)CC)C(=O)CC)CC(=O)O

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CA1 P00915 5/20 0.31
CA2 P00918 5/20 0.31
CA12 O43570 2/20 0.31
CA9 Q16790 2/20 0.31
CA4 P22748 2/20 0.30
DNM1 Q05193 1/20 0.30
KDM4A O75164 1/20 0.30
HIF1A Q16665 1/20 0.30
TET2 Q6N021 1/20 0.30
DOHH Q9BU89 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12581441 1.00 MEN1 (0.32) MEN1KMT2ACA1CA2CA12
SCHEMBL12347474 1.00 MEN1 (0.32) MEN1KMT2ACA1CA2CA12
SCHEMBL19929072 0.88 MEN1 (0.32) MEN1KMT2ADNM1KDM4AHIF1A
SCHEMBL17816490 0.85 FFAR3 (0.36) KMT2A
SCHEMBL12019197 0.85 CA1 (0.31) CA1CA2CA12CA9CA4
SCHEMBL27003678 0.84 MEN1 (0.33) MEN1KMT2ADNM1KDM4AHIF1A
SCHEMBL23394798 0.82
SCHEMBL14473178 0.82
SCHEMBL8281103 0.77 L3MBTL1 (0.34) MEN1KMT2ACA2CA12CA9
SCHEMBL22758076 0.76 MEN1 (0.32) MEN1KMT2ADNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8450469-B2 Synthesis of peptide nucleic acids conjugated with amino acids and their application PANAGENE INC. (KR) 2013-05-28 US disclosed
US-8133985-B2 Peptide nucleic acids conjugated with multi-amine linkers and nucleic acid detecting device using the same PANAGENE INC. (KR) 2012-03-13 US disclosed
US-20110014715-A1 Synthesis of Peptide Nucleic Acids Conjugated with Amino Acids and Their Application PANAGENE INC. (KR) 2011-01-20 US disclosed
US-20090312197-A1 PEPTIDE NUCLEIC ACIDS CONJUGATED WITH MULTI-AMINE LINKERS AND NUCLEIC ACID DETECTING DEVICE USING THE SAME PANAGENE INC. (KR) 2009-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090312197-A1 PEPTIDE NUCLEIC ACIDS CONJUGATED WITH MULTI-AMINE LINKERS AND NUCLEIC ACID DETECTING DEVICE USING THE SAME NPPA, PARN, PARG MEN1 858/4885KMT2A 548/4885CA1 727/4885
US-20110014715-A1 Synthesis of Peptide Nucleic Acids Conjugated with Amino Acids and Their Application CPSF6, RNGTT, DNPEP MEN1 4198/4885KMT2A 1168/4885CA1 1000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.