SCHEMBL19929428

SCHEMBL19929428

C=CC(=O)OCOc1ccc(OC(=O)C#Cc2ccc(COC(=O)C=C)cc2)cc1OCOC(=O)C=C

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 6/20 0.37
ACACB O00763 2/20 0.35
THRB P10828 3/20 0.33
RAB9A P51151 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19929427 0.92 THRB (0.36) FFAR1ACACBTHRB
SCHEMBL19929426 0.92 FFAR1 (0.37) FFAR1ACACBTHRB
SCHEMBL19759395 0.90 THRB (0.36) ACACBTHRBMAPT
SCHEMBL19771197 0.90 THRB (0.32) FFAR1ACACBTHRB
SCHEMBL16426195 0.89 FFAR1 (0.41) FFAR1ACACBTHRBRAB9A
SCHEMBL19759392 0.88 APP (0.36) ACACBTHRBRAB9AMAPT
SCHEMBL19759390 0.88 L3MBTL1 (0.34) FFAR1ACACBTHRB
SCHEMBL19759244 0.88 THRB (0.33) FFAR1THRB
SCHEMBL15397361 0.86 FFAR1 (0.39) FFAR1ACACBTHRBRAB9A
SCHEMBL19759258 0.85 KDM4E (0.34) ACACBTHRBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180112022-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC MATERIAL DIC CORPORATION (JP) 2018-04-26 US disclosed
US-20180066189-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DIC CORPORATION (JP) 2018-03-08 US disclosed