Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24443006 | 0.86 | HRH4 (0.30) | — | |
| SCHEMBL20445471 | 0.76 | MAPT (0.38) | — | |
| SCHEMBL152691 | 0.76 | — | — | |
| SCHEMBL25566663 | 0.73 | PRMT1 (0.46) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL18910977 | 0.73 | — | — | |
| SCHEMBL562464 | 0.73 | TRPV4 (0.33) | — | |
| SCHEMBL12478500 | 0.72 | TRPV4 (0.33) | — | |
| SCHEMBL21227291 | 0.72 | TRPV4 (0.33) | — | |
| SCHEMBL25132445 | 0.71 | PRMT3 (0.44) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL6357556 | 0.70 | TRPV4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3290419-A1 | FUSED-RING OR TRICYCLIC ARYL PYRIMIDINE COMPOUND USED AS KINASE INHIBITOR | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2018-03-07 | — | — | EP | disclosed |