Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11417957 | 0.85 | MAPT (0.48) | ENPP2MAPTNPC1HTTTHRB | |
| SCHEMBL11417961 | 0.85 | MAPT (0.48) | ENPP2MAPTNPC1HTTTHRB | |
| SCHEMBL11421712 | 0.82 | MAPT (0.45) | ENPP2MAPTNPC1HTTTHRB | |
| SCHEMBL14004209 | 0.82 | ENPP2 (0.60) | ENPP2MAPTNPC1HTTAMY1A | |
| SCHEMBL11421726 | 0.82 | MAPT (0.45) | ENPP2MAPTNPC1HTTTHRB | |
| SCHEMBL14704207 | 0.82 | MAPT (0.45) | ENPP2MAPTNPC1HTTTHRB | |
| SCHEMBL11694170 | 0.81 | MAPT (0.49) | ENPP2MAPTNPC1HTTTHRB | |
| SCHEMBL11694161 | 0.81 | MAPT (0.49) | ENPP2MAPTNPC1HTTTHRB | |
| SCHEMBL11677888 | 0.78 | MAPT (0.43) | ENPP2MAPTNPC1HTTTHRB | |
| SCHEMBL11122110 | 0.78 | MAPT (0.49) | ENPP2MAPTNPC1HTTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2846848-B1 | OPHTHALMIC VISCOELASTIC DEVICE | ZEISS CARL MEDITEC AG (DE) | 2018-03-07 | — | — | EP | disclosed |