Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11694161 | 1.00 | MAPT (0.49) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL14704207 | 0.89 | MAPT (0.45) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL11211658 | 0.83 | RECQL (0.48) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL11211648 | 0.83 | RECQL (0.48) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL11417957 | 0.82 | MAPT (0.48) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL11417961 | 0.82 | MAPT (0.48) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL14004209 | 0.81 | ENPP2 (0.60) | MAPTALDH1A1HTTPOLBNPC1 | |
| SCHEMBL19930482 | 0.81 | ENPP2 (0.47) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL11421726 | 0.79 | MAPT (0.45) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL11421712 | 0.79 | MAPT (0.45) | MAPTKMT2AALDH1A1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2846848-B1 | OPHTHALMIC VISCOELASTIC DEVICE | ZEISS CARL MEDITEC AG (DE) | 2018-03-07 | — | — | EP | disclosed |
| US-20150119356-A1 | Ophthalmic Viscoelastic Device | CARL ZEISS MEDITEC AG (DE) | 2015-04-30 | — | — | US | disclosed |
| US-4058607-A | DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES | AIRWICK INDUSTRIES, INC. (US) | 1977-11-15 | — | — | US | disclosed |
| US-3966900-A | INSECTICIDES | AIRWICK INDUSTRIES, INC. (US) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119356-A1 | Ophthalmic Viscoelastic Device | UACA, ICAM1, VIM | MAPT 499/4885KMT2A 3415/4885ALDH1A1 1235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.