Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.69 |
| ▸ | CNR1 | P21554 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1989820 | 0.91 | GHSR (0.78) | GHSRCNR1CNR2HDAC1MEN1 | |
| SCHEMBL1992706 | 0.88 | GHSR (0.72) | GHSRHDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL1992391 | 0.88 | GHSR (0.72) | GHSRHDAC1ALDH1A1HSD17B10MAPK1 | |
| SCHEMBL1989790 | 0.88 | GHSR (0.72) | GHSRHDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL1996335 | 0.88 | GHSR (0.72) | GHSRCYP3A4HDAC1ALDH1A1HSD17B10 | |
| SCHEMBL1990507 | 0.87 | GHSR (0.69) | GHSRCNR1CNR2HDAC1HDAC3 | |
| SCHEMBL1984635 | 0.87 | GHSR (0.69) | GHSRCNR1CNR2CYP2C19CYP2D6 | |
| SCHEMBL1991593 | 0.86 | GHSR (0.70) | GHSRCYP3A4HDAC1ALDH1A1HSD17B10 | |
| SCHEMBL1983537 | 0.86 | GHSR (0.74) | GHSRCNR2HDAC1ALDH1A1HSD17B10 | |
| SCHEMBL1709709 | 0.84 | GHSR (0.66) | GHSRCNR1CNR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152232-A1 | SULFONAMIDE COMPOUNDS AND USES THEREOF | SAUNDERS JEFFREY O | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152232-A1 | SULFONAMIDE COMPOUNDS AND USES THEREOF | GHSR, GHRHR, SSTR2 | GHSR 1/4885CNR1 459/4885CNR2 371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.