Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 19/20 | 0.71 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19930682 | 0.87 | BRD4 (0.53) | BRD4 | |
| SCHEMBL19930751 | 0.86 | BRD4 (0.73) | BRD4BRD9 | |
| SCHEMBL16651168 | 0.83 | BRD4 (1.00) | BRD4TSHR | |
| SCHEMBL21915803 | 0.82 | BRD4 (0.68) | BRD4BRD9 | |
| SCHEMBL19930676 | 0.75 | BRD4 (0.60) | BRD4BRD9 | |
| SCHEMBL19930634 | 0.74 | BRD4 (0.47) | BRD4SMN1; SMN2 | |
| SCHEMBL19930836 | 0.73 | BRD4 (0.53) | BRD4 | |
| SCHEMBL19931487 | 0.73 | BRD4 (0.73) | BRD4BRD9 | |
| SCHEMBL16651183 | 0.70 | BRD4 (1.00) | BRD4 | |
| SCHEMBL16651367 | 0.69 | BRD4 (0.77) | BRD4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4134364-A2 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |
| EP-3640241-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-04-22 | — | — | EP | disclosed |
| EP-3290407-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc (US) | 2018-03-07 | — | — | EP | disclosed |