Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17266546 | 0.78 | ALDH1A1 (0.38) | CYP3A4CASP1RECQLTP53BACE1 | |
| SCHEMBL25043082 | 0.77 | MAOB (0.47) | CYP3A4CASP1RECQLBACE1ALDH1A1 | |
| SCHEMBL7362589 | 0.74 | ALDH1A1 (0.40) | CYP3A4TP53ALDH1A1KDM4EMAOA | |
| SCHEMBL30426786 | 0.74 | CYP3A4 (0.46) | CYP3A4CASP1RECQLTP53BACE1 | |
| SCHEMBL926391 | 0.74 | CYP3A4 (0.46) | CYP3A4CASP1RECQLTP53BACE1 | |
| SCHEMBL18757779 | 0.73 | CYP3A4 (0.41) | CYP3A4CASP1RECQLTP53BACE1 | |
| SCHEMBL18757473 | 0.73 | CYP3A4 (0.41) | CYP3A4CASP1RECQLTP53BACE1 | |
| SCHEMBL24254542 | 0.73 | CYP3A4 (0.41) | CYP3A4CASP1RECQLTP53BACE1 | |
| Bromide SCHEMBL11192117 | 0.73 | ALDH1A1 (0.39) | CYP3A4TP53ALDH1A1KDM4EMAOA | |
| Hydrochloric Acid SCHEMBL2651523 | 0.72 | CYP3A4 (0.44) | CYP3A4CASP1RECQLTP53BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4134364-A2 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |
| EP-3640241-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-04-22 | — | — | EP | disclosed |
| EP-3290407-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc (US) | 2018-03-07 | — | — | EP | disclosed |