Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 20/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19933332 | 1.00 | ADORA2B (0.61) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL19923971 | 0.93 | ADORA2B (0.68) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL19923973 | 0.93 | ADORA2B (0.68) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL18097143 | 0.90 | ADORA2B (0.75) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL18097145 | 0.90 | ADORA2B (0.75) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL20015070 | 0.89 | ADORA2B (0.56) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL19927739 | 0.88 | ADORA2B (0.46) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL19933326 | 0.88 | ADORA2B (0.46) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL18096924 | 0.88 | ADORA2B (0.62) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL19924027 | 0.88 | ADORA2B (0.62) | ADORA2BADORA2AADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018041771-A1 | (1-METHYLCYCLOPROPYL)METHYL-SUBSTITUTED THIENOURACILES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-03-08 | — | — | WO | disclosed |