Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 19/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19923971 | 1.00 | ADORA2B (0.68) | ADORA2BADORA2AADORA1ADORA3MAPK1 | |
| SCHEMBL18097143 | 0.96 | ADORA2B (0.75) | ADORA2BADORA2AADORA1ADORA3MAPK1 | |
| SCHEMBL18097145 | 0.96 | ADORA2B (0.75) | ADORA2BADORA2AADORA1ADORA3MAPK1 | |
| SCHEMBL19924126 | 0.93 | ADORA2B (0.60) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL19924127 | 0.93 | ADORA2B (0.60) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL19924027 | 0.93 | ADORA2B (0.62) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL18096924 | 0.93 | ADORA2B (0.62) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL19933333 | 0.93 | ADORA2B (0.61) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL19924054 | 0.93 | ADORA2B (0.61) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL19933332 | 0.93 | ADORA2B (0.61) | ADORA2BADORA2AADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10428083-B2 | Heterocyclylmethyl-thienouracile as antagonists of the adenosine-A2B-receptor | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-10-01 | — | — | US | disclosed |
| US-20180065981-A1 | HETEROCYCLYLMETHYL-THIENOURACILE AS ANTAGONISTS OF THE ADENOSINE-A2B-RECEPTOR | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-03-08 | — | — | US | disclosed |
| US-20180065981-A1 | HETEROCYCLYLMETHYL-THIENOURACILE AS ANTAGONISTS OF THE ADENOSINE-A2B-RECEPTOR | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065981-A1 | HETEROCYCLYLMETHYL-THIENOURACILE AS ANTAGONISTS OF THE ADENOSINE-A2B-RECEPTOR | ADORA2A, ADORA2B, ADORA3 | ADORA2B 2/4885ADORA2A 1/4885ADORA1 5/4885 |
| US-10428083-B2 | Heterocyclylmethyl-thienouracile as antagonists of the adenosine-A2B-receptor | ADORA2A, ADORA2B, ADORA3 | ADORA2B 2/4885ADORA2A 1/4885ADORA1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.