Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 7/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19101752 | 0.82 | CHRM2 (0.38) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL29308581 | 0.81 | CHRM2 (0.47) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL19934329 | 0.81 | CHRM2 (0.47) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL6944371 | 0.78 | CHRM2 (0.33) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL6951975 | 0.78 | CHRM2 (0.33) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL30891555 | 0.75 | CHRM2 (0.43) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL12513405 | 0.75 | CHRNB2 (0.40) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL30093764 | 0.74 | CHRM2 (0.40) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL14141163 | 0.73 | CHRM2 (0.52) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL6653691 | 0.73 | CHRM2 (0.52) | CHRM2CHRM1CHRM4CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766660-B1 | CYCLOHEXANONE DERIVATIVES, METHOD OF PREPARING THEM AND INTERMEDIATES USED IN THE METHOD | SCHERING AG (DE) | 1999-12-29 | — | — | EP | claimed |
| EP-0766660-A1 | CYCLOHEXANONE DERIVATIVES, METHOD OF PREPARING THEM AND INTERMEDIATES USED IN THE METHOD | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-04-09 | — | — | EP | claimed |
| WO-1996000207-A1 | CYCLOHEXANONE DERIVATIVES, METHOD OF PREPARING THEM AND INTERMEDIATES USED IN THE METHOD | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-01-04 | — | — | WO | claimed |
| EP-0766660-B1 | CYCLOHEXANONE DERIVATIVES, METHOD OF PREPARING THEM AND INTERMEDIATES USED IN THE METHOD | SCHERING AG (DE) | 1999-12-29 | — | — | EP | disclosed |
| US-5886233-A | Cyclohexanone derivatives, process for their production and intermediate products of the process | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | disclosed |