Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | PLEKHA1 | Q9HB21 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 9/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL148462 | 0.81 | AKT1 (0.49) | KMT2APOLBALDH1A1AKT1BTK | |
| SCHEMBL18043741 | 0.81 | AKT1 (0.49) | KMT2APOLBALDH1A1AKT1BTK | |
| Hydrochloric Acid SCHEMBL26923029 | 0.79 | AKT1 (0.51) | KMT2APOLBALDH1A1AKT1BTK | |
| SCHEMBL20653616 | 0.79 | AKT1 (0.40) | KMT2APOLBALDH1A1AKT1BTK | |
| Hydrochloric Acid SCHEMBL26921279 | 0.79 | AKT1 (0.51) | KMT2APOLBALDH1A1AKT1BTK | |
| SCHEMBL22063459 | 0.77 | KMT2A (0.56) | KMT2APOLBALDH1A1AKT1BTK | |
| SCHEMBL179213 | 0.71 | — | — | |
| SCHEMBL15307887 | 0.68 | AKT1 (0.49) | KMT2APOLBALDH1A1AKT1BTK | |
| SCHEMBL12034489 | 0.68 | AKT1 (0.49) | KMT2APOLBALDH1A1AKT1BTK | |
| SCHEMBL16706556 | 0.68 | KMT2A (0.39) | KMT2APOLBALDH1A1AKT1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11046679-B2 | Indoleamine 2,3-dioxygenase inhibitor and application | NANJING TRANSTHERA BIOSCIENCES CO. LTD. (CN) | 2021-06-29 | — | — | US | disclosed |
| US-20200181131-A1 | INDOLEAMINE 2,3-DIOXYGENASE INHIBITOR AND APPLICATION | NANJING TRANSTHERA BIOSCIENCES CO. LTD. (CN) | 2020-06-11 | — | — | US | disclosed |
| WO-2018044663-A1 | NOVEL SUBSTITUTED N'-HYDROXYCARBAMIMIDOYL-1,2,5-OXADIAZOLE COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE (IDO) INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2018-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11046679-B2 | Indoleamine 2,3-dioxygenase inhibitor and application | IDO1, IDO2, INMT | KMT2A 92/4885POLB 4137/4885ALDH1A1 1320/4885 |
| US-20200181131-A1 | INDOLEAMINE 2,3-DIOXYGENASE INHIBITOR AND APPLICATION | IDO1, IDO2, INMT | KMT2A 92/4885POLB 4137/4885ALDH1A1 1320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.