Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 9/20 | 0.45 |
| ▸ | NPC1 | O15118 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 2/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | PLEKHA1 | Q9HB21 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14592144 | 0.80 | KMT2A (0.53) | KMT2APKML3MBTL1RAB9ANPC1 | |
| SCHEMBL150406 | 0.80 | AKT1 (0.55) | KMT2APKML3MBTL1RAB9ANPC1 | |
| SCHEMBL14592141 | 0.80 | AKT1 (0.55) | KMT2APKML3MBTL1RAB9ANPC1 | |
| SCHEMBL5350096 | 0.80 | KMT2A (0.53) | KMT2APKML3MBTL1RAB9ANPC1 | |
| SCHEMBL122211 | 0.80 | AKT1 (0.55) | KMT2APKML3MBTL1RAB9ANPC1 | |
| SCHEMBL22672833 | 0.78 | KMT2A (0.51) | KMT2APKML3MBTL1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL20983704 | 0.78 | AKT1 (0.58) | KMT2APKML3MBTL1RAB9ANPC1 | |
| SCHEMBL19934375 | 0.77 | KMT2A (0.42) | KMT2APKML3MBTL1ALDH1A1IDO1 | |
| SCHEMBL10181686 | 0.75 | KMT2A (0.49) | KMT2APKML3MBTL1RAB9ANPC1 | |
| SCHEMBL5359902 | 0.74 | KMT2A (0.47) | KMT2APKML3MBTL1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11046679-B2 | Indoleamine 2,3-dioxygenase inhibitor and application | NANJING TRANSTHERA BIOSCIENCES CO. LTD. (CN) | 2021-06-29 | — | — | US | disclosed |
| US-20200361919-A1 | DEUTERATED INDOLEAMINE 2,3-DIOXYGENASE INHIBITOR AND APPLICATION THEREOF | NANJING TRANSTHERA BIOSCIENCES CO. LTD. (CN) | 2020-11-19 | — | — | US | disclosed |
| US-20200181131-A1 | INDOLEAMINE 2,3-DIOXYGENASE INHIBITOR AND APPLICATION | NANJING TRANSTHERA BIOSCIENCES CO. LTD. (CN) | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11046679-B2 | Indoleamine 2,3-dioxygenase inhibitor and application | IDO1, IDO2, INMT | KMT2A 92/4885PKM 1122/4885L3MBTL1 3647/4885 |
| US-20200181131-A1 | INDOLEAMINE 2,3-DIOXYGENASE INHIBITOR AND APPLICATION | IDO1, IDO2, INMT | KMT2A 92/4885PKM 1122/4885L3MBTL1 3647/4885 |
| US-20200361919-A1 | DEUTERATED INDOLEAMINE 2,3-DIOXYGENASE INHIBITOR AND APPLICATION THEREOF | IDO1, IDO2, INMT | KMT2A 224/4885PKM 1662/4885L3MBTL1 3024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.