Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | BMP1 | P13497 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 5/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 8/20 | 0.33 |
| ▸ | MMP3 | P08254 | 3/20 | 0.33 |
| ▸ | MME | P08473 | 4/20 | 0.32 |
| ▸ | CPA1 | P15085 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19934771 | 0.95 | ACE (0.44) | ACEBMP1MMP9MMP2MMP8 | |
| SCHEMBL19934757 | 0.91 | ACE (0.43) | ACEBMP1MMP9MMP2MMP8 | |
| SCHEMBL21134710 | 0.91 | BMP1 (0.46) | ACEBMP1MMP9MMP2MMP8 | |
| SCHEMBL19934754 | 0.91 | BMP1 (0.46) | ACEBMP1MMP9MMP2MMP8 | |
| SCHEMBL19934701 | 0.91 | BMP1 (0.46) | ACEBMP1MMP9MMP2MMP8 | |
| SCHEMBL19934743 | 0.91 | BMP1 (0.46) | ACEBMP1MMP9MMP2MMP8 | |
| SCHEMBL19934696 | 0.91 | BMP1 (0.46) | ACEBMP1MMP9MMP2MMP8 | |
| SCHEMBL21135087 | 0.91 | BMP1 (0.46) | ACEBMP1MMP9MMP2MMP8 | |
| SCHEMBL21153275 | 0.91 | BMP1 (0.46) | ACEBMP1MMP9MMP2MMP8 | |
| SCHEMBL19934735 | 0.91 | BMP1 (0.46) | ACEBMP1MMP9MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508476-B1 | AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION | SHANGHAI KECHOW PHARMA INC (CN) | 2023-11-22 | — | — | EP | disclosed |
| EP-3984993-A1 | USE OF AMINOTHIOL COMPOUNDS AS CEREBRAL NERVE OR HEART PROTECTIVE AGENT | Shanghai Kechow Pharma, Inc. (CN) | 2022-04-20 | — | — | EP | disclosed |
| EP-3508476-A1 | AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION | Inst Of Radiation Medicine Chinese Acad Of Medical Sciences (CN) | 2019-07-10 | — | — | EP | disclosed |
| WO-2018041245-A1 | AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION | 中国医学科学院放射医学研究所 | 2018-03-08 | — | — | WO | disclosed |