Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 4/20 | 0.45 |
| ▸ | PRKCB | P05771 | 11/20 | 0.42 |
| ▸ | PRKCA | P17252 | 11/20 | 0.42 |
| ▸ | PRKCG | P05129 | 10/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 6/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.42 |
| ▸ | CAMK2B | Q13554 | 3/20 | 0.42 |
| ▸ | CAMK2G | Q13555 | 3/20 | 0.42 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | PRKCH | P24723 | 2/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 13/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | PRKACA | P17612 | 2/20 | 0.39 |
| ▸ | PRKACG | P22612 | 2/20 | 0.39 |
| ▸ | PRKACB | P22694 | 2/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1992218 | 0.92 | CAMK2D (0.49) | CAMK2DPRKCBPRKCAPRKCGPRKCD | |
| SCHEMBL1995677 | 0.91 | CAMK2D (0.49) | CAMK2DPRKCBPRKCAPRKCGPRKCD | |
| SCHEMBL1990609 | 0.90 | CAMK2D (0.44) | CAMK2DPRKCBPRKCAPRKCGPRKCD | |
| SCHEMBL1997092 | 0.90 | CAMK2D (0.44) | CAMK2DPRKCBPRKCAPRKCGPRKCD | |
| SCHEMBL1999866 | 0.90 | CAMK2D (0.44) | CAMK2DPRKCBPRKCAPRKCGPRKCD | |
| SCHEMBL1997361 | 0.89 | CAMK2D (0.45) | CAMK2DPRKCBPRKCAPRKCGPRKCD | |
| SCHEMBL1990076 | 0.88 | CAMK2D (0.48) | CAMK2DPRKCBPRKCAPRKCGPRKCD | |
| SCHEMBL1997364 | 0.88 | CAMK2D (0.47) | CAMK2DPRKCBPRKCAPRKCGPRKCD | |
| SCHEMBL1991812 | 0.88 | CAMK2D (0.45) | CAMK2DPRKCBPRKCAPRKCGPRKCD | |
| SCHEMBL1992095 | 0.87 | CAMK2D (0.43) | CAMK2DPRKCBPRKCAPRKCGPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079105-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-30 | — | — | WO | disclosed |
| WO-2011079105-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-30 | — | — | WO | disclosed |
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | CAMK2D 2963/4885PRKCB 3335/4885PRKCA 3438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.