SCHEMBL19935503

SCHEMBL19935503

CCOC(=O)c1ccc(C(=O)Nc2ccc(N=Nc3ccc(N(C)C)cc3)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 11/20 0.65
MAPT P10636 8/20 0.65
NPC1 O15118 7/20 0.65
ALDH1A1 P00352 7/20 0.65
SMN1; SMN2 Q16637 7/20 0.65
LMNA P02545 5/20 0.65
MAPK1 P28482 3/20 0.65
GAA P10253 3/20 0.62
L3MBTL1 Q9Y468 4/20 0.59
TSHR P16473 4/20 0.56
KDM4E B2RXH2 2/20 0.56
MCL1 Q07820 2/20 0.56
HSD17B10 Q99714 2/20 0.56
NPSR1 Q6W5P4 2/20 0.55
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
TDP1 Q9NUW8 1/20 0.54
TP53 P04637 3/20 0.53
POLB P06746 1/20 0.52
HTT P42858 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19930182 1.00 RAB9A (0.65) RAB9AMAPTNPC1ALDH1A1SMN1; SMN2
SCHEMBL8747958 0.92 RAB9A (0.74) RAB9AMAPTNPC1ALDH1A1SMN1; SMN2
SCHEMBL18821733 0.88 NPC1 (0.70) RAB9AMAPTNPC1ALDH1A1SMN1; SMN2
SCHEMBL5879030 0.83 RAB9A (0.88) RAB9AMAPTNPC1ALDH1A1SMN1; SMN2
SCHEMBL10943445 0.83 RAB9A (0.88) RAB9AMAPTNPC1ALDH1A1SMN1; SMN2
SCHEMBL19930169 0.81 PRSS1 (0.61) RAB9AMAPTNPC1ALDH1A1SMN1; SMN2
SCHEMBL10892520 0.80 KCNK3 (0.65) RAB9AMAPTNPC1ALDH1A1SMN1; SMN2
SCHEMBL10892514 0.80 KCNK3 (0.65) RAB9AMAPTNPC1ALDH1A1SMN1; SMN2
SCHEMBL5190217 0.80 ALDH1A1 (0.70) RAB9AMAPTNPC1ALDH1A1SMN1; SMN2
SCHEMBL15425 0.80 ALDH1A1 (0.70) RAB9AMAPTNPC1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200264460-A1 POLARIZING PLATE AND CIRCULARLY POLARIZING PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-08-20 US disclosed
US-10690953-B2 Polarizing plate and circularly polarizing plate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-06-23 US disclosed
US-20180067348-A1 POLARIZING PLATE AND CIRCULARLY POLARIZING PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-03-08 US disclosed