Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20202534 | 0.95 | EPHX2 (0.53) | LPAR1EPHX2SLC6A5CNR1KDM4E | |
| SCHEMBL25030622 | 0.95 | EPHX2 (0.53) | LPAR1EPHX2SLC6A5CNR1KDM4E | |
| SCHEMBL12295581 | 0.91 | EPHX2 (0.49) | LPAR1EPHX2SLC6A5CNR1KDM4E | |
| SCHEMBL31720955 | 0.88 | CNR1 (0.45) | LPAR1EPHX2SLC6A5CNR1FAAH | |
| SCHEMBL17776037 | 0.85 | EPHX2 (0.56) | LPAR1EPHX2SLC6A5CNR1KDM4E | |
| SCHEMBL18973140 | 0.85 | EPHX2 (0.51) | LPAR1EPHX2SLC6A5CNR1KDM4E | |
| SCHEMBL23735528 | 0.84 | EPHX2 (0.53) | LPAR1EPHX2SLC6A5CNR1KDM4E | |
| SCHEMBL14035358 | 0.84 | CNR1 (0.63) | LPAR1EPHX2SLC6A5CNR1KDM4E | |
| SCHEMBL15362884 | 0.83 | ALDH1A1 (0.54) | LPAR1EPHX2SLC6A5CNR1KDM4E | |
| SCHEMBL25793510 | 0.83 | CASP2 (0.55) | LPAR1EPHX2SLC6A5FAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018044350-A1 | TARGETING LIGANDS | ARROWHEAD PHARMACEUTICALS, INC (US) | 2018-03-08 | — | — | WO | disclosed |