Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.55 |
| ▸ | CASP2 | P42575 | 1/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | SELP | P16109 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21582897 | 0.92 | CASP2 (0.57) | FAAHCASP2DNM1LPAR1CNR1 | |
| SCHEMBL21761818 | 0.92 | FAAH (0.65) | FAAHCASP2DNM1LPAR1CNR1 | |
| SCHEMBL15597179 | 0.92 | CNR1 (0.51) | FAAHCASP2DNM1LPAR1CNR1 | |
| SCHEMBL9549395 | 0.90 | FAAH (0.68) | FAAHCASP2DNM1LPAR1NAAA | |
| SCHEMBL118328 | 0.90 | FAAH (0.68) | FAAHCASP2DNM1LPAR1NAAA | |
| SCHEMBL23005324 | 0.90 | FAAH (0.68) | FAAHCASP2DNM1LPAR1NAAA | |
| SCHEMBL114457 | 0.90 | FAAH (0.68) | FAAHCASP2DNM1LPAR1NAAA | |
| SCHEMBL18738989 | 0.90 | FAAH (0.68) | FAAHCASP2DNM1LPAR1NAAA | |
| SCHEMBL115888 | 0.90 | FAAH (0.68) | FAAHCASP2DNM1LPAR1NAAA | |
| SCHEMBL27360878 | 0.90 | FAAH (0.68) | FAAHCASP2DNM1LPAR1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018044350-A1 | TARGETING LIGANDS | ARROWHEAD PHARMACEUTICALS, INC (US) | 2018-03-08 | — | — | WO | disclosed |