Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | FABP2 | P12104 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19308568 | 0.91 | DHODH (0.43) | DHODHMAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL10091190 | 0.90 | MAPT (0.49) | DHODHHPRT1MAPTLMNAHTT | |
| SCHEMBL10091182 | 0.90 | MAPT (0.49) | DHODHHPRT1MAPTLMNAHTT | |
| SCHEMBL10091268 | 0.86 | NPC1 (0.45) | HPRT1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL18553010 | 0.85 | ESR2 (0.49) | HPRT1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL18069661 | 0.84 | PTGS2 (0.43) | SMN1; SMN2MEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL12315382 | 0.84 | PTGS2 (0.44) | DHODHMAPTTDP1PDK2CYP1A2 | |
| SCHEMBL21386565 | 0.83 | DHODH (0.39) | DHODHMAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL13156763 | 0.83 | PDE3B (0.37) | DHODHPDK2PTGS1PTGS2AKR1C4 | |
| SCHEMBL172359 | 0.82 | PDE3B (0.47) | MAPTLMNAHTTSMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935513-B1 | LIQUID-CRYSTALLINE MEDIA, COMPONENTS FOR HIGH-FREQUENCY TECHNOLOGY, AND MESOGENIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2018-03-07 | — | — | EP | disclosed |