Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16221904 | 0.81 | — | — | |
| SCHEMBL23621946 | 0.80 | EPHX1 (0.42) | EPHX1PAOXSIGMAR1HTR2AHRH1 | |
| SCHEMBL12321237 | 0.77 | EPHX1 (0.39) | EPHX1PAOXKISS1RSIGMAR1HTR2A | |
| SCHEMBL2363326 | 0.77 | ADH1B (0.46) | EPHX1 | |
| SCHEMBL23279316 | 0.76 | KISS1R (0.37) | EPHX1PAOXKISS1RHTR2AHRH1 | |
| SCHEMBL25729920 | 0.75 | — | — | |
| SCHEMBL5613606 | 0.75 | TSHR (0.44) | — | |
| SCHEMBL5613583 | 0.75 | TSHR (0.44) | — | |
| SCHEMBL10555437 | 0.75 | TSHR (0.44) | — | |
| SCHEMBL1157220 | 0.75 | TSHR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018045245-A1 | CYCLIC PEPTIDE ANALOGS AND CONJUGATES THEREOF | SIRENAS LLC (US) | 2018-03-08 | — | — | WO | disclosed |