Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.84 |
| ▸ | ICMT | O60725 | 11/20 | 0.69 |
| ▸ | HTR1A | P08908 | 1/20 | 0.67 |
| ▸ | HTR7 | P34969 | 1/20 | 0.67 |
| ▸ | HTR6 | P50406 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12541297 | 1.00 | OPRM1 (0.84) | OPRM1ICMTHTR1AHTR7HTR6 | |
| SCHEMBL12541950 | 0.93 | OPRM1 (0.81) | OPRM1ICMTHTR1AHTR7HTR6 | |
| SCHEMBL19027193 | 0.92 | OPRM1 (0.72) | OPRM1ICMTHTR1AHTR7HTR6 | |
| SCHEMBL12542194 | 0.92 | OPRM1 (1.00) | OPRM1ICMTHTR1AHTR7HTR6 | |
| SCHEMBL18899397 | 0.92 | OPRM1 (1.00) | OPRM1ICMTHTR1AHTR7HTR6 | |
| SCHEMBL13546107 | 0.90 | OPRM1 (0.70) | OPRM1ICMTHTR1AHTR7HTR6 | |
| SCHEMBL12692092 | 0.90 | ICMT (0.73) | OPRM1ICMTHTR1AHTR7HTR6 | |
| SCHEMBL13546103 | 0.87 | MEN1 (0.68) | OPRM1ICMTHTR1AHTR7HTR6 | |
| SCHEMBL18886985 | 0.86 | OPRM1 (0.71) | OPRM1ICMTHTR1AHTR7HTR6 | |
| SCHEMBL19937060 | 0.85 | ICMT (0.71) | OPRM1ICMTHTR1AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3290415-A1 | OPIOID RECEPTOR LIGANDS AND METHODS OF USING AND MAKING SAME | Trevena, Inc. (US) | 2018-03-07 | — | — | EP | disclosed |